Our Constitution is designed only for a moral and religious people. It is wholly inadequate for any other.
Slightly over 200 years later, there are people who insist that our Constitution is a wholly secular document that "liberates" us from the constraints of morality, particularly if that morality arises from religious convictions. And especially if those convictions have Christian undertones. That assumption, however, contradicts Adams' statement.
Unlike many evangelicals of my generation, I'm not adamant that the United States of America was founded as a specifically as a Christian nation. But I do believe our Founding Fathers wanted our country to reflect Biblical values. Obviously John Adams had no intention of completely isolating the nation from morality and religion! It's time to be the type of people that Adams described!